Journal of Emergency Nursing
Volume 36, Issue 1 , Pages 26-28 , January 2010

Administration of Amiodarone During Resuscitation of Ventricular Arrhythmias

  • Heather D. Eppert, PharmD, BCPS

      Affiliations

    • Corresponding Author InformationFor correspondence, write: Heather D. Eppert, PharmD, BCPS, 1924 Alcoa Highway, Box 117, Knoxville, TN 37920
    • ,
  • Kara B. Goddard, BS

References 

  1. Scheinman MM, Levine JH, Cannom DS, et al. Dose-ranging study of intravenous amiodarone in patients with life-threatening ventricular tachyarrhythmias. Circulation. 1995;92:3264–3272
  2. Levine JH, Massumi A, Scheinman MM, et al. Intravenous amiodarone for recurrent sustained hypotensive ventricular tachyarrhythmias. J Am Coll Cardiol. 1996;27:67–75
  3. Helmy I, Herre JM, Gee G, et al. Use of intravenous amiodarone for emergency treatment of life-threatening ventricular arrhythmias. J Am Coll Cardiol. 1988;12:1615–1622
  4. Morady F, Scheinman MM, Shen E, Shapiro W, Sung RJ, DiCarlo L. Intravenous amiodarone in the acute treatment of recurrent symptomatic ventricular tachycardia. Am J Cardiol. 1983;51:156–159
  5. Mostow ND, Rakita L, Vrobel TR, et al. Amiodarone: intravenous loading for rapid suppression of complex ventricular arrhythmias. J Am Coll Cardiol. 1984;4:97–104
  6. Leak D. Intravenous amiodarone in the treatment of refractory life-threatening cardiac arrhythmias in the critically ill patient. Am Heart J. 1986;111:456–462
  7. Klein RC, Machell C, Rushforth N, Standefur J. Efficacy of intravenous amiodarone as short-term treatment for refractory ventricular tachycardia. Am Heart J. 1988;115:96–101
  8. Schutzenberger W, Leisch F, Kerschner K, et al. Clinical efficacy of intravenous amiodarone in the short term treatment of recurrent sustained ventricular tachycardia and ventricular fibrillation. Br Heart J. 1989;62:367–371
  9. Williams ML, Woelfel A, Cascio W, et al. Intravenous amiodarone during prolonged resuscitation from cardiac arrest. Ann Intern Med. 1989;110:839–842
  10. Ochi RP, Goldenberg IF, Almquist A, et al. Intravenous amiodarone for the rapid treatment of life-threatening ventricular arrhythmias in critically ill patients with coronary artery disease. Am J Cardiol. 1989;64:599–603
  11. Mooss AN, Mohiuddin SM, Hee TT, et al. Efficacy and tolerance of high-dose intravenous amiodarone for recurrent, refractory ventricular tachycardia. Am J Cardiol. 1990;65:609–614
  12. Nalos PC, Ismail Y, Pappas JM, et al. Intravenous amiodarone for short-term treatment of refractory ventricular tachycardia or fibrillation. Am Heart J. 1991;122:1629–1632
  13. Kowey PR, Levine JG, Herre JM, et al. Randomized, double-blind comparison of intravenous amiodarone and bretylium in the treatment of patients with recurrent, hemodynamically destabilizing ventricular tachycardia or fibrillation. Circulation. 1995;92:3255–3263
  14. Dorian P, Cass D, Schwartz B, Cooper R, Gelaznikas R, Barr A. Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation. N Engl J Med. 2002;346:884–890
  15. Kudenchuk PJ, Cobb LA, Copass MK, et al. Amiodarone for resuscitation after out-of-hospital cardiac arrest due to ventricular fibrillation. N Engl J Med. 1999;341:871–878
  16. Emergency Cardiovascular Care Committee, Subcommittees, and Task Forces of the American Heart Association. 2005 Guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2005;112(suppl I):I1–I211
  17. Cordarone (amiodarone hydrochloride) [product information]. Philadelphia, PA: Wyeth-Ayerst Company; 2001;
  18. Skrifvars MB, Kuisma M, Boyd J, et al. The use of undiluted amiodarone in the management of out-of-hospital cardiac arrest. Acta Anesthesiol Scand. 2004;48:582–587
  19. Remme WJ, Kruyssen HACM, Look MP, et al. Hemodynamic effects and tolerability of intravenous amiodarone in patients with impaired left ventricular function. Am Heart J. 1991;122:96–103
  20. Gonzalez ER, Kannewurf BS, Ornato JP. Intravenous amiodarone for ventricular arrhythmias: overview and clinical use. Resuscitation. 1998;39:33–42

 Earn Up to 8 CE Hours. See page 88.

PII: S0099-1767(09)00240-2

doi: 10.1016/j.jen.2009.05.022

Journal of Emergency Nursing
Volume 36, Issue 1 , Pages 26-28 , January 2010

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